As 生物科学代谢部主管 for 心血管, 肾与代谢(CVRM), 我监督和指导澳门葡京赌博游戏的战略, seeking to underst和 the role of metabolism in illness. This includes participating in the core strategy team 和 business development activities, 和 being a champion for inclusion 和 diversity.
Altered metabolic processes play a key part in all CVRM diseases 和 underst和ing these changes can be critical in finding effective treatments. My role involves working closely with teams across all of our research sites 和 CVRM research programmes. We have a diverse research portfolio, spanning from target investigations to phase 2b studies in diseases such as diabetes, 肥胖, non-alcoholic liver diseases 和 dyslipidaemia (high lipids in the blood).
I received my PhD in Physiology 和 Pharmacology from the University of Nottingham Medical School 和 have worked for many years in the field of drug discovery including work on muscle disorders, 肥胖和糖尿病, 两者都用 在活的有机体内 和 在体外 方法. I have been working consistently across CVRM diseases since 2014.
Effective teamworking is vital to successful drug development. It is important that colleagues can benefit from a range of skills, communicate effectively 和 underst和 each other. My experience in collaborative team building 和 leadership extends across academia 和 industry, including both scientific leadership 和 people development. The collaborations I facilitate enable teams across the business 和 beyond to generate high-impact science that drives the discovery of life-changing medicines.
Science is at the forefront of our decision-making 和 I am proud to work for a company that champions scientists, supporting cross-industry collaboration to drive innovation. It is incredibly rewarding to mentor research rising stars, providing them with the opportunity to grow, 成功, 并最终, 为患者改变治疗结果.
![大卫•贝克, Head of Metabolism Bioscience, CVRM.](/content/dam/az/our-company/our-people/DavidBaker-banner.jpg/jcr:content/renditions/cq5dam.web.100.square.DavidBaker-banner.jpg)
电流的作用
2019年至今
2017 – 2019
2014 – 2017
2012 – 2014
2009 – 2012
科学出版物
Human genetics uncovers MAP3K15 as an 肥胖-independent therapeutic target for diabetes.
Nag A, Dhindsa R, Mitchell J, 等. 科学的进步2022年11月8日(46)
Controlling the bioactivity of a peptide hormone 在活的有机体内 by reversible self-assembly
Ouberai MM, Gomes Dos Santos AL, Kinna S, 等. 学报8,1026 (2017)
Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake 和 preference in mice
Lewis JE, Woodward OR, Nuzzaci D 等. 摩尔金属底座. 2022年12月. 66: 101604
Veeva ID: Z4-52290
Date of preparation: February 2023